Top 5 Most Dangerous Diabetes Drugs

Posted by on Jul 24, 2015 in Doctors, Hospitals |

Oral medications for diabetes are a part of many individuals’ daily routine globally. Apparently, these medications can control diabetes by suppressing its symptoms so as to sustain the life of a patient, if used in accordance with medical guidelines.

However, going by the latest discovery, some of these drugs seem to be injurious to your health rather than beneficial. More and more lawsuits are being filed against manufacturers of prescription diabetes medications. Many patients have complained of having suffered severe side effects after taking some of these drugs.

It has been unearthed that there are certain diabetes medications which can lead to detrimental health consequences if they are used for a long period of time even if it is in the manner which was prescribed. Therefore, we have compiled this article to warn you against some of these drugs and expose everything some manufacturers don’t want you to know and with that we believe you can stay safe. The following is a list of top 5 most dangerous diabetes drugs on the market.

1) Pioglitazone

Also known as ‘ACTOS’, Pioglitazone is an oral pill intended for patients with type 2 diabetes. It is distributed by Eli Lilly and Company but manufactured by Takeda Pharmaceuticals. Although this drug is usually marketed as helping to control blood sugar levels, it is far from what it seems!

ACTOS has been put under the microscope by the U.S Food and Drug Administration for quite some time now due to its life threatening side effects including bladder cancer and heart failure.

After testing it, the FDA found that, the risk of bladder cancer increased with the increasing dosage and duration of its use. Along with this risk, in 2011, they also warned that patients who are taking this drug are 40% more susceptible to bladder cancer than their counterparts who are not. Other possible severe side effects discovered were heart failure, painful urination, blurry vision, weight gain and jaundice.

Due to this, the US food and drug regulatory body ordered Takeda Pharmaceuticals to include a warning on the drug’s label. The new label warns that the usage of the drug for more than 12 months may lead to bladder cancer and other symptoms stated above.

Another study spearheaded by epidemiologist Dr. Laurent Azoulay and involving 116,000 patients’ records in the UK was conducted in Canada .Again; the results confirmed that patients who took the drug for more than 2 years are twice as likely to develop bladder cancer. Due to these potential side effects, it was banned in Germany and France in 2011.

ACTOS was once a top-selling diabetes drug in the US and the rest of the world, but today consumers have significantly shunned it.

2) Rosiglitazone Maleate

Also known as Avandia, Rosiglitazone Maleate is a drug manufactured by GlaxoSmithKline and intended for Type 2 diabetes patients. It has been around since 1999, and was once a bestselling type 2 diabetes drug, generating an annual revenue of more than $2 billion by 2006. The sales drastically dropped when possible Avandia adverse side effects, including heart problems became known. In spite of this, Avandia is still popular in the US.

Patients who are undergoing insulin therapy must never take this drug. A study by the FDA in 2006, involving 227,571 patients concluded disturbing results; 14% are likely to die, 25% are likely to develop heart problems and 27% of the patients are likely to develop stroke! According to several clinical studies, Avandia is linked to as many as 100,000 heart attack cases. Today, the number of victims of Avandia’s side effects continues to grow, and so are the lawsuits filed against GlaxoSmithKline.

3) Byetta

Rolled out in 2005 and distributed by Bristol-Myers Squibb and AstraZeneca, Byetta is a medication intended for patients suffering from type 2 diabetes. It comes in an injectable form. Although it seems potent, this drug has life threatening side effects not to mention pancreatic cancer! In spite of this fatal risk, health practitioners continue to prescribe it.

The drug works by inhibiting the increase of blood glucose in the stomach, hampering its release from the liver. It then rouses the insulin-producing cells in the pancreas which then produce more insulin.

Immediately after the Food and Drug Administration had approved this diabetes drug in 2005, there were alleged reports claiming it is linked to pancreatitis and by October 2007, the FDA issued its first warning to consumers against Byetta when 30 users were diagnosed with severe pancreatitis. They noted headache, dizziness, drowsiness, weakness, diarrhea, vomiting, jitters, confusion, irritability, hunger, palpitation as the drug’s minor adverse effects.

i)Byetta should not be taken as alternative to insulin.
ii) It should not be taken by patients who have serious kidney problems.

If you have been affected by the drug’s serious side effects, it is imperative that you seek legal redress from the manufacturer with the help of an experienced legal expert.

4) Sitagliptin Phosphate

Also known as Januvia, Sitagliptin Phosphate is a medication created by Merck & Co for Type 2 Diabetes patients. It works by decreasing sugar in the liver while encouraging the pancreas to produce more insulin.

First approved as a class of dipeptidyl peptidase-4 (DPP-4) inhibitor in October 2006, this drug is today linked to kidney problems, hypoglycemia, thyroid cancer, pancreas inflammation and many other health complications.

Sitagliptin Phosphate should only be taken once in a day, and shouldn’t to be used for patients with Type 1 diabetes.

5) Statins

Statins is a group of costly drugs intended for diabetic people. They work by lowering LDL cholesterol which in some scientific explanation ends up controlling symptoms of diabetes. Examples of Statins approved in the U.S. include:


Although these drugs are approved by the FDA, they are actually not safe. Statins have both minor and major side effects with the latter including muscle damage, brain damage and permanent memory loss, increased insulin resistance and so on.


As you can see, there are so many dangerous diabetes drugs on the market today. If you have suffered any major side effect from any of these drugs, don’t let it go. You need to be compensated for the damage just like others. An experienced attorney can help you to sue for damages and get compensated fast.

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Taking Zofran For Nausea Or Morning Sickness Might Increase Risk For Zofran Birth Defects

Posted by on Jul 5, 2015 in Doctors, Tips for Childbirth |

A recent study is questioning just how safe Zofran is. The popular nausea and morning sickness drug is prescribed to pregnant women at times, but findings suggest that Zofran increases risk of injury to the mother and severe Zofran birth defects to her infant.

Zofran is manufactured by GlaxoSmithKline. It is a 5-HT3 receptor antagonist that is also available as ondnsetron, which is the generic form. It works through affecting the serotonin levels inside the brain. It was first approved in 1991 for treating vomiting and nausea following surgery and in cancer patients. However, it continues to be prescribed by doctors “off-label” to pregnant women to treat vomiting and nausea.

A study conducted by Dr. Gideon Koren that appeared in the American Journal of Obstetrics and Gynecology in December 2014 highlighted the risks that pregnant woman may experience from taking Zofran as well as the conflicting studies that do not rule out the the fetus may also be in danger. Koren is affiliated with the University of Toronto, The Hospital for Sick Children and the Motherrisk Program.

Zofran Birth Defects

In August 2013 the study involving 900,000 Danish women found a 2-fold increase in risk for cardiac malformations when taking ondansetron (Zofran), which leads to a 30 percent overall increased risk for major congenital malformations.

Approximately 80 percent of women suffer from nausea and vomiting when pregnant. According to Koren, approximately 1 million pregnant women take Zofran or the generic version each year.

Zofran was also compared to metoclopramide in the study, which is another drug that is used for treating nausea and vomiting in pregnancy (NVP). During the first trimester there was not an association between metoclopramide and birth defects. According to the authors of the study, there are other FDA-approved NPV treatments that are safer, such as pyridoxine and doxylamine.

According to Koren, there is no reason to expose women to a drug with unproven fetal a maternal safety, when safer options are available.

Conflicting Data

No safety issues were found with Zofran birth defects in earlier studies. However, more recent research suggests that the earlier data might not have been accurate enough for drawing good conclusions.

For example, a smaller and earlier study involving 176 women did not find a connection between malformations and the drug. However, due to the small sample size, it was unable to detect a risk of less than three-fold. So possibility of risk could not actually be ruled out.

In February 2013 a study appeared in the New England Journal of Medicine that involved 2,000 women that appeared on a Danish birth registry between 2004 and 2011. The study found that harm to fetuses was not posed by the medication. However, half of the study’s subjects start to take the drug at around 10 weeks into their pregnancy- which is past the time when malformations develop. The data was believed to be sound by doctors.

Several months later, Danish researchers presented their findings at an International Society of Pharmacoepidemiology meeting. Their evidence was collected from 13 years worth of data. The findings from the study showed that 58 out of 1,248 women taking ondansetron during their first trimester had babies with a birth defect, which represented a 30 percent increased in risk.

$3 Billion Paid By Glaxo To Settle Allegations Of Fraud

One very real side effect of the questionable safety of Zofran is the lawsuits, both civil and federal. GlaxoSmithKline was sued by the Department of Justice for unlawful promotion as well as failing to report safety data on several of its drugs, which included Zofran recall. In response, Glaxo plead guilty to the charge of promoting the drug illegally for treating morning sickness, and agreed in 2012 to pay $3 billion to settle the charges.

Families with infants who were born with a Zofran birth defect due to Zofran are also suing the drug company. There is no safety warning on the drug label about birth defects.

Women who used Zofran during their pregnancies gave birth to infants with Zofran birth defects, which included heart defects, club feet, cleft lips and palates as well as craniosynostosis- which is a condition where the skull has an abnormal shape and might not provide sufficient space for the brain. It can cause mental impairment, eating issues and vision problems.

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10 Tips to Help You Prepare for Childbirth and Labor

Posted by on Jul 4, 2015 in Doctors, Hospitals, Tips for Childbirth |

If you are pregnant, you may be looking up for some information to help you have a healthy pregnancy, and of course, you may also be looking for ways to make labor easier and some natural and safe ways to help you go through childbirth easily. Indeed, pregnancy is a very crucial stage of motherhood and almost all women want to choose giving birth naturally – without the many drugs involved. Of course, you can also help yourself to make your labor and delivery easier.

10 Tips to Help You Prepare for Childbirth and Labor

Secure support

Doulas are nonmedical experts prepared to give passionate and physical backing and data to ladies amid pregnancy and work. Studies have found that with a prepared doula’s consistent bolster, work times are shorter and the requirement for epidurals, C-segments, oxytocin for prompting and forceps were diminished by about half. Another study inferred that ladies who got bolster through a doctor’s facility based doula project were more prone to endeavor breastfeeding. Look at DONA International to help you find an affirmed doula in your general vicinity.

Have a trap up your sleeve

Realize a few viable procedures to oversee agony amid labor, for example, self-entrancing, position changes, warmth pack application and diverse breathing strategies.

Get on up

imagesUpright positions, for example, standing, strolling, stooping, moderate moving, sitting and crouching, permit gravity to help move the infant crestfallen. “Here and there, getting the child into the pelvis is similar to fitting a key into a lock,” Hartley says. “You have to do a touch of shaking. Shaking forward and backward staring you in the face and knees may help to get the infant into position.”

Set the scene

For most ladies, a dull and calm environment is perfect amid work, so ask your medical caretaker or accomplice to diminish the lights and minimize clamor. Little touches have any kind of effect: a most loved pad, pair of socks or mitigating fragrance. “Fragrance based treatment, particularly the aroma of lavender, is exceptionally quieting in labor,” says Miya.

It would be best for you to avoid taking any medication listed here, as some have been linked to serious birth defects.  Consult your doctor before taking any medication while pregnant.

Be a water child

The glow and weightlessness of a shower can be alleviating all through your work, so on the off chance that you have entry to a warm tub, take the dive. (Make sure to get your specialist or birthing assistant’s green light before doing as such; there’s a danger of contamination if your water has broken.)

In the event that a splash isn’t conceivable, take a stab at scrubbing down.

Stay consistent with yourself

Work changes you, yet it won’t make you abruptly love lime Jell-O, New Age music or seeing your in-laws as you inhale through a compression. Individuals may push a wide range of recommendations on you amid work; listen however don’t feel you need to oblige them.

– Learn some unwinding procedures.

Birth-checklistSetting yourself up for labor means honing yourself to unwind so you can center and take make work simpler. Figuring out how to unwind notwithstanding amid the first phases of your pregnancy can for sure help you rehearse until labor. One of the procedures that can help you practice to unwind is to learn stomach breathing which is additionally a decent procedure in helping you remember pressure in the muscles encompassing the guts that you would doubtlessly worry amid work. You can likewise rehearse symbolism to utilize the force of your psyche to unwind and stay centered.

– Find support.

One of the numerous things that can likewise make your work less demanding is to have family and companions for backing. The father of your youngster is regularly the best bolster that you can have amid work. Have some trusted loved ones that can help you stay positive and quiet amid your work. Obviously, it helps a great deal to have the right individuals next to you who can run errands and who can urge you to make work less demanding.

– Finding the right practice for you.

childbirth456Practicing throughout your pregnancy is to be sure a decent help to make work simpler. Moderate to direct paced strolling is one of the best activities you can do while pregnant. It can likewise help to get dynamic amid the early phases of work and do some strolling to help your pelvis move to make more space for the child. Getting dynamic amid the early indications of work can likewise help get your brain off the agony.

– Acupressure for instigating work actually.

On the off chance that you are past your evaluated conveyance date and you require a little help, it is in fact great to choose normal approaches to impel work, yet you must be additional cautious in verifying that it is alright for you and your infant. Pressure point massage is one approach to help you actuate work in the meantime help you unwind. In pressure point massage, weight focuses like the webbing in the middle of your thumb and pointers are empowered to give you compressions. Then again, it is imperative to note that utilizing regular systems as a part of affecting work are simply compelling in the event that you are past due or your cervix is ready or prepared for work.

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